I am running 2 HVR-1600 (thats 4 tuners 2 cable (analog) and 2 digital (Free OTA HD) right now with no issues on the same antenna.
If I were to do it over I would have one
HVR-1600 and one
HVR-1800. Why? Because the 1800 has FM radio built right into it which configs with vista durring setup and its a PCIexpress X1 card, for me that frees up a standard PCI card slot.