As long as your remote is a X10 device it should work fine. The
ActiveHome scripting libraries used by X10Commander works on all X10 devices.
Did you enable logging (see the checkbox in the lower-left corner of X10Commander)?
What device driver is your remote using? From Device Manager (My Computer>Properties>Hardware>Device Manager), double-click the RW2 device under USB controllers and go to Driver, then Driver Details. Your device driver should be X10*.sys (e.g. mine is X10ufx2.sys).
You could also check that you have a C:\Program Files\Common Files\X10 folder.